It would be hard to pinpoint one reason why the colonists

went to war against England for their independence. 

It was more like a series of events that led to the reasons for the

American Revolution.

My mind goes back to the French and Indian War. 

The Reaction:
They tried to settle this dispute peacefully. But they could not.
The French and Indian War was declared. 
The French and Indians fought together against the English colonists from 1754 until 1763. 
England helped the colonists during the war. 
In the end, the colonists were victorious.